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Protein data
function: oxidoreductaseexperiment: X-RAY DIFFRACTION
resolution: 2.6 Å
origomeric count: 2
axial ligand #1: CYS
chainID: C,resSeq: 422,
Coordination distance[Å]: 2.172
molecule: LANOSTEROL 14-ALPHA-DEMETHYLASE
EC number: 1.14.13.70
Organism: TRYPANOSOMA BRUCEI
axial ligand #2: X2N
chainID: C,resSeq: 1479,
Coordination distance[Å]: 1.901
molecule: POSACONAZOLE
List of other hemes in pdb:2x2n
ID of heme | Distortion | Axial ligands on heme | Function & structure | |
---|---|---|---|---|
2x2n-A-1479![]() |
sad. -0.08 ruf. -0.67 dom. -0.24 bre. +0.01 |
CYS | chainID: A, resSeq: 422, molecule: LANOSTEROL 14-ALPHA-DEMETHYLASE |
oxidoreductase oligomeric count: 2 pocket vol.: 403.0 Å3 d(Fe-oop): 0.056 Å |
X2N | chainID: A, resSeq: 1480, molecule: POSACONAZOLE |
|||
2x2n-B-1478![]() |
sad. +0.05 ruf. -0.60 dom. -0.15 bre. +0.03 |
CYS | chainID: B, resSeq: 422, molecule: LANOSTEROL 14-ALPHA-DEMETHYLASE |
oxidoreductase oligomeric count: 2 pocket vol.: 407.0 Å3 d(Fe-oop): 0.104 Å |
X2N | chainID: B, resSeq: 1479, molecule: POSACONAZOLE |
|||
2x2n-D-1478![]() |
sad. -0.23 ruf. -0.69 dom. -0.13 bre. +0.04 |
CYS | chainID: D, resSeq: 422, molecule: LANOSTEROL 14-ALPHA-DEMETHYLASE |
oxidoreductase oligomeric count: 2 pocket vol.: 417.0 Å3 d(Fe-oop): 0.050 Å |
X2N | chainID: D, resSeq: 1479, molecule: POSACONAZOLE |