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PyDISH No: 17933

PDB: 8sg5,
chainID: D, resSeq: 601
heme type: B

distortion

Protein data

function: oxidoreductase
experiment: X-RAY DIFFRACTION
resolution: 2.8 Å

axial ligand #1: CYS

chainID: D,
resSeq: 441,
Coordination distance[Å]: 2.31
molecule: Cytochrome P450 3A5
EC number: 1.14.14.1
Organism: Homo sapiens

axial ligand #2: CL6

chainID: D,
resSeq: 602,
Coordination distance[Å]: 2.084
molecule: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE

List of other hemes in pdb:8sg5

ID of heme	Distortion	Axial ligands on heme		Function & structure
8sg5-A-601	`sad. -0.24 ruf. -0.33 dom. +0.07 bre. -0.01`	CYS	chainID: A, resSeq: 441, molecule: Cytochrome P450 3A5	oxidoreductase oligomeric count: 1 pocket vol.: 419.0 Å³ d(Fe-oop): 0.056 Å
8sg5-A-601	`sad. -0.24 ruf. -0.33 dom. +0.07 bre. -0.01`	CL6	chainID: A, resSeq: 602, molecule: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE
8sg5-B-601	`sad. -0.27 ruf. -0.03 dom. +0.07 bre. -0.01`	CYS	chainID: B, resSeq: 441, molecule: Cytochrome P450 3A5	oxidoreductase oligomeric count: 1 pocket vol.: 422.0 Å³ d(Fe-oop): 0.064 Å
8sg5-B-601	`sad. -0.27 ruf. -0.03 dom. +0.07 bre. -0.01`	CL6	chainID: B, resSeq: 602, molecule: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE
8sg5-C-601	`sad. -0.28 ruf. -0.26 dom. +0.08 bre. -0.01`	CYS	chainID: C, resSeq: 441, molecule: Cytochrome P450 3A5	oxidoreductase oligomeric count: 1 pocket vol.: 419.0 Å³ d(Fe-oop): 0.066 Å
8sg5-C-601	`sad. -0.28 ruf. -0.26 dom. +0.08 bre. -0.01`	CL6	chainID: C, resSeq: 602, molecule: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE
8sg5-E-601	`sad. -0.27 ruf. -0.18 dom. +0.03 bre. -0.01`	CYS	chainID: E, resSeq: 441, molecule: Cytochrome P450 3A5	oxidoreductase oligomeric count: 1 pocket vol.: 415.0 Å³ d(Fe-oop): 0.083 Å
8sg5-E-601	`sad. -0.27 ruf. -0.18 dom. +0.03 bre. -0.01`	CL6	chainID: E, resSeq: 602, molecule: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE
8sg5-F-601	`sad. -0.30 ruf. -0.03 dom. +0.13 bre. -0.01`	CYS	chainID: F, resSeq: 441, molecule: Cytochrome P450 3A5	oxidoreductase oligomeric count: 1 pocket vol.: 418.0 Å³ d(Fe-oop): 0.055 Å
8sg5-F-601	`sad. -0.30 ruf. -0.03 dom. +0.13 bre. -0.01`	CL6	chainID: F, resSeq: 602, molecule: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE
8sg5-G-601	`sad. -0.31 ruf. +0.04 dom. +0.11 bre. -0.00`	CYS	chainID: G, resSeq: 441, molecule: Cytochrome P450 3A5	oxidoreductase oligomeric count: 1 pocket vol.: 423.0 Å³ d(Fe-oop): 0.070 Å
8sg5-G-601	`sad. -0.31 ruf. +0.04 dom. +0.11 bre. -0.00`	CL6	chainID: G, resSeq: 602, molecule: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE
8sg5-H-601	`sad. -0.27 ruf. +0.23 dom. +0.04 bre. -0.02`	CYS	chainID: H, resSeq: 441, molecule: Cytochrome P450 3A5	oxidoreductase oligomeric count: 1 pocket vol.: 445.0 Å³ d(Fe-oop): 0.076 Å
8sg5-H-601	`sad. -0.27 ruf. +0.23 dom. +0.04 bre. -0.02`	CL6	chainID: H, resSeq: 602, molecule: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE