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Protein data
function: oxidoreductaseexperiment: X-RAY DIFFRACTION
resolution: 2.11 Å
axial ligand #1: CYS
chainID: B,resSeq: 430,
Coordination distance[Å]: 2.315
molecule: Protein CYP51
Organism: Naegleria fowleri
axial ligand #2: 7PW
chainID: B,resSeq: 502,
Coordination distance[Å]: 2.036
molecule: N-[(1R)-2-(1H-imidazol-1-yl)-1-(3,4',5-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide
List of other hemes in pdb:7rtq
ID of heme | Distortion | Axial ligands on heme | Function & structure | |
---|---|---|---|---|
7rtq-A-501![]() |
sad. -0.23 ruf. -0.36 dom. +0.08 bre. +0.01 |
CYS | chainID: A, resSeq: 430, molecule: Protein CYP51 |
oxidoreductase oligomeric count: 1 pocket vol.: 465.0 Å3 d(Fe-oop): 0.042 Å |
7PW | chainID: A, resSeq: 502, molecule: N-[(1R)-2-(1H-imidazol-1-yl)-1-(3,4',5-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide |
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7rtq-C-501![]() |
sad. -0.26 ruf. -0.29 dom. +0.08 bre. +0.00 |
CYS | chainID: C, resSeq: 430, molecule: Protein CYP51 |
oxidoreductase oligomeric count: 1 pocket vol.: 478.0 Å3 d(Fe-oop): 0.045 Å |
7PW | chainID: C, resSeq: 502, molecule: N-[(1R)-2-(1H-imidazol-1-yl)-1-(3,4',5-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide |
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7rtq-D-501![]() |
sad. -0.17 ruf. -0.36 dom. +0.01 bre. -0.00 |
CYS | chainID: D, resSeq: 430, molecule: Protein CYP51 |
oxidoreductase oligomeric count: 1 pocket vol.: 456.0 Å3 d(Fe-oop): 0.042 Å |
7PW | chainID: D, resSeq: 502, molecule: N-[(1R)-2-(1H-imidazol-1-yl)-1-(3,4',5-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide |