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PyDISH No: 15246

PDB: 7lu7,
chainID: BBB, resSeq: 401
heme type: B

distortion

Protein data

function: oxidoreductase
experiment: X-RAY DIFFRACTION
resolution: 2.3 Å

axial ligand #1: HIS

chainID: BBB,
resSeq: 328,
Coordination distance[Å]: 1.993
molecule: Tryptophan 2,3-dioxygenase
EC number: 1.13.11.11
Organism: Homo sapiens

axial ligand #2: 5PK

chainID: AAA,
resSeq: 404,
Coordination distance[Å]: 1.879
molecule: (1~{R})-1-cyclohexyl-2-[(5~{S})-5~{H}-imidazo[1,5-b]isoindol-5-yl]ethanol

List of other hemes in pdb:7lu7

ID of heme	Distortion	Axial ligands on heme		Function & structure
7lu7-AAA-401	`sad. +0.11 ruf. -0.63 dom. -0.08 bre. +0.04`	HIS	chainID: AAA, resSeq: 328, molecule: Tryptophan 2,3-dioxygenase	oxidoreductase oligomeric count: 4 pocket vol.: 504.0 Å³ d(Fe-oop): 0.052 Å
7lu7-AAA-401	`sad. +0.11 ruf. -0.63 dom. -0.08 bre. +0.04`	5PK	chainID: AAA, resSeq: 403, molecule: (1~{R})-1-cyclohexyl-2-[(5~{S})-5~{H}-imidazo[1,5-b]isoindol-5-yl]ethanol
7lu7-CCC-401	`sad. +0.01 ruf. -0.59 dom. -0.09 bre. +0.01`	HIS	chainID: CCC, resSeq: 328, molecule: Tryptophan 2,3-dioxygenase	oxidoreductase oligomeric count: 4 pocket vol.: 476.0 Å³ d(Fe-oop): 0.007 Å
7lu7-CCC-401	`sad. +0.01 ruf. -0.59 dom. -0.09 bre. +0.01`	5PK	chainID: CCC, resSeq: 403, molecule: (1~{R})-1-cyclohexyl-2-[(5~{S})-5~{H}-imidazo[1,5-b]isoindol-5-yl]ethanol
7lu7-DDD-401	`sad. +0.05 ruf. -0.61 dom. -0.08 bre. +0.04`	HIS	chainID: DDD, resSeq: 328, molecule: Tryptophan 2,3-dioxygenase	oxidoreductase oligomeric count: 4 pocket vol.: 475.0 Å³ d(Fe-oop): 0.002 Å
7lu7-DDD-401	`sad. +0.05 ruf. -0.61 dom. -0.08 bre. +0.04`	5PK	chainID: DDD, resSeq: 403, molecule: (1~{R})-1-cyclohexyl-2-[(5~{S})-5~{H}-imidazo[1,5-b]isoindol-5-yl]ethanol