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Protein data
function: oxidoreductaseexperiment: X-RAY DIFFRACTION
resolution: 2.306 Å
axial ligand #1: HIS
chainID: D,resSeq: 346,
Coordination distance[Å]: 2.072
molecule: Indoleamine 2,3-dioxygenase 1
EC number: 1.13.11.52
Organism: Homo sapiens
axial ligand #2: BBJ
chainID: D,resSeq: 502,
Coordination distance[Å]: 1.789
molecule: N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide
List of other hemes in pdb:6e40
| ID of heme | Distortion | Axial ligands on heme | Function & structure | |
|---|---|---|---|---|
6e40-A-501 |
sad. +0.30 ruf. +0.36 dom. -0.07 bre. -0.25 |
HIS | chainID: A, resSeq: 346, molecule: Indoleamine 2,3-dioxygenase 1 |
oxidoreductase oligomeric count: 1 pocket vol.: 499.0 Å3 d(Fe-oop): 0.039 Å |
| BBJ | chainID: A, resSeq: 502, molecule: N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide |
|||
6e40-B-501 |
sad. +0.38 ruf. +0.63 dom. -0.19 bre. -0.09 |
HIS | chainID: B, resSeq: 346, molecule: Indoleamine 2,3-dioxygenase 1 |
oxidoreductase oligomeric count: 1 pocket vol.: 502.0 Å3 d(Fe-oop): 0.120 Å |
| BBJ | chainID: B, resSeq: 502, molecule: N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide |
|||
6e40-C-501 |
sad. +0.41 ruf. +0.49 dom. -0.06 bre. -0.22 |
HIS | chainID: C, resSeq: 346, molecule: Indoleamine 2,3-dioxygenase 1 |
oxidoreductase oligomeric count: 1 pocket vol.: 518.0 Å3 d(Fe-oop): 0.264 Å |
| Not assigned. | ||||