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Protein data
function: oxidoreductaseexperiment: X-RAY DIFFRACTION
resolution: 2.65 Å
origomeric count: 4
axial ligand #1: HIS
chainID: A,resSeq: 328,
Coordination distance[Å]: 1.897
molecule: Tryptophan 2,3-dioxygenase
EC number: 1.13.11.11
Organism: Homo sapiens
axial ligand #2: 9R9
chainID: A,resSeq: 402,
Coordination distance[Å]: 2.096
molecule: 1-(6-chloro-1H-indazol-4-yl)cyclohexan-1-ol
List of other hemes in pdb:6a4i
ID of heme | Distortion | Axial ligands on heme | Function & structure | |
---|---|---|---|---|
6a4i-B-401![]() |
sad. -0.15 ruf. -0.24 dom. +0.28 bre. -0.01 |
HIS | chainID: B, resSeq: 328, molecule: Tryptophan 2,3-dioxygenase |
oxidoreductase oligomeric count: 4 pocket vol.: 474.0 Å3 d(Fe-oop): 0.006 Å |
9R9 | chainID: B, resSeq: 402, molecule: 1-(6-chloro-1H-indazol-4-yl)cyclohexan-1-ol |
|||
6a4i-C-401![]() |
sad. -0.30 ruf. -0.83 dom. +0.24 bre. +0.09 |
HIS | chainID: C, resSeq: 328, molecule: Tryptophan 2,3-dioxygenase |
oxidoreductase oligomeric count: 4 pocket vol.: 442.0 Å3 d(Fe-oop): 0.009 Å |
9R9 | chainID: C, resSeq: 402, molecule: 1-(6-chloro-1H-indazol-4-yl)cyclohexan-1-ol |
|||
6a4i-D-401![]() |
sad. -0.07 ruf. -0.30 dom. +0.36 bre. -0.05 |
HIS | chainID: D, resSeq: 328, molecule: Tryptophan 2,3-dioxygenase |
oxidoreductase oligomeric count: 4 pocket vol.: 515.0 Å3 d(Fe-oop): 0.005 Å |
9R9 | chainID: D, resSeq: 402, molecule: 1-(6-chloro-1H-indazol-4-yl)cyclohexan-1-ol |