Browser
Protein data
function: oxidoreductaseexperiment: X-RAY DIFFRACTION
resolution: 2.91 Å
origomeric count: 1
axial ligand #1: CYS
chainID: E,resSeq: 441,
Coordination distance[Å]: 2.238
molecule: Cytochrome P450 3A5
EC number: 1.14.14.1
Organism: Homo sapiens
List of other hemes in pdb:5veu
| ID of heme | Distortion | Axial ligands on heme | Function & structure | |
|---|---|---|---|---|
5veu-A-601 |
sad. -0.06 ruf. +0.07 dom. +0.03 bre. -0.21 |
CYS | chainID: A, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 429.0 Å3 d(Fe-oop): 0.017 Å |
| RIT | chainID: A, resSeq: 602, molecule: RITONAVIR |
|||
5veu-B-601 |
sad. +0.10 ruf. +0.15 dom. -0.09 bre. -0.21 |
CYS | chainID: B, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 415.0 Å3 d(Fe-oop): 0.032 Å |
| RIT | chainID: B, resSeq: 602, molecule: RITONAVIR |
|||
5veu-C-601 |
sad. -0.02 ruf. -0.02 dom. -0.00 bre. -0.22 |
CYS | chainID: C, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 410.0 Å3 d(Fe-oop): 0.007 Å |
| Not assigned. | ||||
5veu-D-601 |
sad. -0.07 ruf. +0.00 dom. +0.04 bre. -0.22 |
CYS | chainID: D, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 417.0 Å3 d(Fe-oop): 0.028 Å |
| Not assigned. | ||||
5veu-F-601 |
sad. -0.07 ruf. -0.01 dom. -0.08 bre. -0.23 |
CYS | chainID: F, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 413.0 Å3 d(Fe-oop): 0.017 Å |
| Not assigned. | ||||
5veu-G-601 |
sad. -0.14 ruf. -0.17 dom. +0.09 bre. -0.21 |
CYS | chainID: G, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 394.0 Å3 d(Fe-oop): 0.002 Å |
| Not assigned. | ||||
5veu-H-601 |
sad. +0.01 ruf. +0.05 dom. -0.11 bre. -0.04 |
CYS | chainID: H, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 415.0 Å3 d(Fe-oop): 0.132 Å |
| RIT | chainID: H, resSeq: 602, molecule: RITONAVIR |
|||
5veu-I-601 |
sad. -0.04 ruf. -0.11 dom. -0.05 bre. -0.22 |
CYS | chainID: I, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 425.0 Å3 d(Fe-oop): 0.002 Å |
| Not assigned. | ||||
5veu-J-601 |
sad. -0.01 ruf. -0.03 dom. +0.17 bre. -0.21 |
CYS | chainID: J, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 407.0 Å3 d(Fe-oop): 0.045 Å |
| Not assigned. | ||||
5veu-K-601 |
sad. -0.05 ruf. +0.01 dom. -0.04 bre. -0.22 |
CYS | chainID: K, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 406.0 Å3 d(Fe-oop): 0.009 Å |
| Not assigned. | ||||
5veu-L-601 |
sad. -0.08 ruf. -0.08 dom. +0.11 bre. -0.22 |
CYS | chainID: L, resSeq: 441, molecule: Cytochrome P450 3A5 |
oxidoreductase oligomeric count: 1 pocket vol.: 427.0 Å3 d(Fe-oop): 0.019 Å |
| Not assigned. | ||||