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Protein data
function: oxidoreductaseexperiment: X-RAY DIFFRACTION
resolution: 3.2 Å
axial ligand #1: CYS
chainID: G,resSeq: 450,
Coordination distance[Å]: 2.797
molecule: Cytochrome P450 11B2, mitochondrial
EC number: 1.14.15.4,1.14.15.5
Organism: Homo sapiens
List of other hemes in pdb:4zgx
| ID of heme | Distortion | Axial ligands on heme | Function & structure | |
|---|---|---|---|---|
4zgx-A-601 |
sad. +0.11 ruf. -0.38 dom. +0.21 bre. +0.08 |
CYS | chainID: A, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 423.0 Å3 d(Fe-oop): 0.202 Å |
| QHC | chainID: A, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-B-601 |
sad. -0.07 ruf. -0.02 dom. +0.20 bre. -0.05 |
CYS | chainID: B, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 392.0 Å3 d(Fe-oop): 0.144 Å |
| QHC | chainID: B, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-C-601 |
sad. +0.07 ruf. -0.13 dom. +0.19 bre. +0.11 |
CYS | chainID: C, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 406.0 Å3 d(Fe-oop): 0.068 Å |
| QHC | chainID: C, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-D-601 |
sad. +0.13 ruf. -0.26 dom. +0.25 bre. +0.10 |
CYS | chainID: D, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 389.0 Å3 d(Fe-oop): 0.156 Å |
| QHC | chainID: D, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-E-601 |
sad. -0.04 ruf. -0.01 dom. +0.15 bre. +0.22 |
CYS | chainID: E, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 417.0 Å3 d(Fe-oop): 0.136 Å |
| QHC | chainID: E, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-F-601 |
sad. -0.01 ruf. -0.16 dom. +0.18 bre. +0.15 |
CYS | chainID: F, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 408.0 Å3 d(Fe-oop): 0.125 Å |
| QHC | chainID: F, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-H-601 |
sad. +0.14 ruf. -0.37 dom. +0.57 bre. +0.25 |
Not assigned. | unclassified oligomeric count: 1 pocket vol.: 436.0 Å3 d(Fe-oop): 0.303 Å |
|
| Not assigned. | ||||
4zgx-I-601 |
sad. -0.16 ruf. -0.41 dom. +0.29 bre. +0.10 |
CYS | chainID: I, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 437.0 Å3 d(Fe-oop): 0.190 Å |
| QHC | chainID: I, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-J-601 |
sad. +0.03 ruf. -0.58 dom. +0.34 bre. +0.14 |
CYS | chainID: J, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 426.0 Å3 d(Fe-oop): 0.204 Å |
| QHC | chainID: J, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-K-601 |
sad. -0.39 ruf. +0.05 dom. +0.02 bre. +0.22 |
CYS | chainID: K, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 413.0 Å3 d(Fe-oop): 0.002 Å |
| QHC | chainID: K, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||
4zgx-L-601 |
sad. -0.18 ruf. -0.50 dom. +0.23 bre. +0.14 |
CYS | chainID: L, resSeq: 450, molecule: Cytochrome P450 11B2, mitochondrial |
oxidoreductase oligomeric count: 1 pocket vol.: 441.0 Å3 d(Fe-oop): 0.156 Å |
| QHC | chainID: L, resSeq: 602, molecule: N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide |
|||