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Protein data
function: oxidoreductaseexperiment: X-RAY DIFFRACTION
resolution: 2.8 Å
origomeric count: 1
axial ligand #1: CYS
chainID: A,resSeq: 442,
Coordination distance[Å]: 2.326
molecule: CYTOCHROME P450 3A4
EC number: 1.14.14.1, 1.14.13.67
Organism: HOMO SAPIENS
axial ligand #2: KLN
chainID: A,resSeq: 1500,
Coordination distance[Å]: 2.097
molecule: 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE
List of other hemes in pdb:2v0m
ID of heme | Distortion | Axial ligands on heme | Function & structure | |
---|---|---|---|---|
2v0m-B-1497![]() |
sad. -0.34 ruf. -0.12 dom. +0.14 bre. -0.29 |
CYS | chainID: B, resSeq: 442, molecule: CYTOCHROME P450 3A4 |
oxidoreductase oligomeric count: 1 pocket vol.: 425.0 Å3 d(Fe-oop): 0.105 Å |
KLN | chainID: B, resSeq: 1498, molecule: 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE |
|||
2v0m-C-1497![]() |
sad. -0.02 ruf. -0.02 dom. -0.03 bre. -0.29 |
CYS | chainID: C, resSeq: 442, molecule: CYTOCHROME P450 3A4 |
oxidoreductase oligomeric count: 1 pocket vol.: 423.0 Å3 d(Fe-oop): 0.096 Å |
KLN | chainID: C, resSeq: 1498, molecule: 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE |
|||
2v0m-D-1497![]() |
sad. -0.09 ruf. -0.05 dom. -0.03 bre. -0.27 |
CYS | chainID: D, resSeq: 442, molecule: CYTOCHROME P450 3A4 |
oxidoreductase oligomeric count: 1 pocket vol.: 398.0 Å3 d(Fe-oop): 0.043 Å |
KLN | chainID: D, resSeq: 1498, molecule: 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE |