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ID of heme Axial ligands on heme Function & structure
7kqu-B-401
sad. -0.17
ruf. -0.03
dom. +0.22
bre. -0.18
HIS chainID: B,
resSeq: 196,
molecule: Heme-dependent L-tyrosine hydroxylase
oxidoreductase
oligomeric count: 2
pocket vol.: 564.0 Å3
d(Fe-oop): 0.134 Å
PEO chainID: B, resSeq: 403,

molecule: HYDROGEN PEROXIDE

7ks8-A-601
sad. -0.23
ruf. +0.13
dom. +0.12
bre. -0.21
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 443.0 Å3
d(Fe-oop): 0.026 Å
Not assigned.
7ksa-A-601
sad. -0.29
ruf. +0.22
dom. +0.22
bre. -0.20
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 420.0 Å3
d(Fe-oop): 0.074 Å
X8P chainID: A, resSeq: 602,

molecule: (tert-butyl {1-[(1-oxo-3-phenyl-1-{[3-(pyridin-3-yl-kappaN)prop-1-en-1-yl]amino}propan-2-yl)sulfanyl]-3-phenylpropan-2-yl}carbamate)(6,6'-dimethyl-2,2'-bipyridine-kappa~2~N~1~,N~1'~)(1~2~,2~2~:2~6~,3~2~-terpyridine-kappa~3~N~1^{1~},N~2^{1~},N~3^{1~})ruthenium

7kvh-A-601
sad. -0.32
ruf. +0.06
dom. +0.29
bre. -0.21
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 382.0 Å3
d(Fe-oop): 0.003 Å
X5Y chainID: A, resSeq: 602,

molecule: tert-butyl [(2S)-1-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate

7kvh-B-601
sad. -0.28
ruf. +0.05
dom. +0.05
bre. -0.22
CYS chainID: B,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 418.0 Å3
d(Fe-oop): 0.014 Å
X5Y chainID: B, resSeq: 602,

molecule: tert-butyl [(2S)-1-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate

7kvi-A-601
sad. -0.13
ruf. +0.37
dom. +0.11
bre. -0.21
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 438.0 Å3
d(Fe-oop): 0.065 Å
X7P chainID: A, resSeq: 603,

molecule: tert-butyl [(2R)-1-{[(2S)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate

7kvj-A-601
sad. -0.19
ruf. +0.19
dom. +0.20
bre. -0.22
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 428.0 Å3
d(Fe-oop): 0.001 Å
X7M chainID: A, resSeq: 602,

molecule: tert-butyl [(2S)-1-{[(2S)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate

7kvk-A-601
sad. -0.26
ruf. +0.25
dom. +0.17
bre. -0.22
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 408.0 Å3
d(Fe-oop): 0.031 Å
X7J chainID: A, resSeq: 602,

molecule: tert-butyl [(2R)-1-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate

7kvk-B-601
sad. -0.20
ruf. +0.01
dom. +0.19
bre. -0.22
CYS chainID: B,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 419.0 Å3
d(Fe-oop): 0.028 Å
X7J chainID: B, resSeq: 603,

molecule: tert-butyl [(2R)-1-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate

7kvm-A-601
sad. -0.10
ruf. +0.22
dom. +0.15
bre. -0.20
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 424.0 Å3
d(Fe-oop): 0.011 Å
X71 chainID: A, resSeq: 602,

molecule: tert-butyl [(2S)-1-{[(2R)-2-benzyl-3-oxo-3-{[3-(pyridin-3-yl)propyl]amino}propyl]sulfanyl}-3-phenylpropan-2-yl]carbamate

7kvn-A-601
sad. -0.32
ruf. +0.00
dom. +0.12
bre. -0.22
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 406.0 Å3
d(Fe-oop): 0.008 Å
X6V chainID: A, resSeq: 602,

molecule: tert-butyl [(2S)-1-(1H-indol-3-yl)-3-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kvn-B-601
sad. -0.19
ruf. +0.18
dom. +0.18
bre. -0.21
CYS chainID: B,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 420.0 Å3
d(Fe-oop): 0.182 Å
X6V chainID: B, resSeq: 602,

molecule: tert-butyl [(2S)-1-(1H-indol-3-yl)-3-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kvo-A-601
sad. -0.23
ruf. +0.02
dom. -0.01
bre. -0.20
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 390.0 Å3
d(Fe-oop): 0.022 Å
X6S chainID: A, resSeq: 603,

molecule: tert-butyl [(2S)-1-(naphthalen-1-yl)-3-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kvo-B-601
sad. -0.31
ruf. -0.31
dom. +0.08
bre. -0.18
CYS chainID: B,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 425.0 Å3
d(Fe-oop): 0.065 Å
X6S chainID: B, resSeq: 602,

molecule: tert-butyl [(2S)-1-(naphthalen-1-yl)-3-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kvp-A-601
sad. -0.19
ruf. +0.14
dom. +0.09
bre. -0.15
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 443.0 Å3
d(Fe-oop): 0.044 Å
X6J chainID: A, resSeq: 602,

molecule: tert-butyl [(2R)-1-(naphthalen-1-yl)-3-{[(2S)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kvq-A-601
sad. -0.29
ruf. +0.15
dom. +0.03
bre. -0.22
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 408.0 Å3
d(Fe-oop): 0.048 Å
X7D chainID: A, resSeq: 607,

molecule: tert-butyl [(2S)-1-(naphthalen-1-yl)-3-{[(2S)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kvq-B-601
sad. -0.24
ruf. -0.04
dom. +0.08
bre. -0.22
CYS chainID: B,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 414.0 Å3
d(Fe-oop): 0.053 Å
X7D chainID: B, resSeq: 602,

molecule: tert-butyl [(2S)-1-(naphthalen-1-yl)-3-{[(2S)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kvs-A-601
sad. -0.31
ruf. +0.08
dom. +0.15
bre. -0.23
CYS chainID: A,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 411.0 Å3
d(Fe-oop): 0.062 Å
X74 chainID: A, resSeq: 605,

molecule: tert-butyl [(2R)-1-(naphthalen-1-yl)-3-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kvs-B-602
sad. -0.32
ruf. -0.10
dom. +0.12
bre. -0.22
CYS chainID: B,
resSeq: 442,
molecule: Cytochrome P450 3A4
oxidoreductase
oligomeric count: 2
pocket vol.: 416.0 Å3
d(Fe-oop): 0.098 Å
X74 chainID: B, resSeq: 603,

molecule: tert-butyl [(2R)-1-(naphthalen-1-yl)-3-{[(2R)-1-oxo-3-phenyl-1-{[3-(pyridin-3-yl)propyl]amino}propan-2-yl]sulfanyl}propan-2-yl]carbamate

7kyr-A-201
sad. +0.01
ruf. -0.00
dom. -0.02
bre. -0.45
HIS chainID: A,
resSeq: 93,
molecule: Myoglobin
oxygen carrier
oligomeric count: 1
pocket vol.: 475.0 Å3
d(Fe-oop): 0.036 Å
HOH chainID: A, resSeq: 331,

molecule: water